USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: H2A1J_HUMAN USC-OGP 2-DE database:  H2A1J_HUMAN H2A1J_HUMAN General information about the entry View entry in simple text format Entry name H2A1J_HUMAN Primary accession number Q99878 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Histone H2A type 1-J; AltName: Full=Histone H2A/e;. Gene name Name=HIST1H2AJ Synonyms=H2AFE Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1333: pI=4.59; Mw=16158 SPOT OGP-1335: pI=5.02; Mw=16085 SPOT OGP-1336: pI=5.13; Mw=15865 Cross-references UniProtKB/Swiss-Prot Q99878; H2A1J_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name H2A1J_HUMAN Primary accession number Q99878 Secondary accession number(s) A2RUU6 Q5JXQ5 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 167) Name and origin of the protein Description RecName: Full=Histone H2A type 1-J; AltName: Full=Histone H2A/e; Gene name Name=HIST1H2AJ Synonyms=H2AFE Encoded on Name=HIST1H2AJ; Synonyms=H2AFE Keywords Acetylation; Chromosome; Citrullination; Complete proteome; DNA-binding; Isopeptide bond; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL Z83736; CAB06031.1; -; Genomic_DNA EMBL AY131990; AAN59971.1; -; Genomic_DNA EMBL AL049822; CAB81656.1; -; Genomic_DNA EMBL CH471081; EAX03109.1; -; Genomic_DNA EMBL BC066232; AAH66232.1; -; mRNA EMBL BC066233; AAH66233.1; -; mRNA EMBL BC066234; AAH66234.1; -; mRNA EMBL BC066235; AAH66235.1; -; mRNA EMBL BC066236; AAH66236.1; -; mRNA EMBL BC066237; AAH66237.1; -; mRNA EMBL BC133048; AAI33049.1; -; mRNA EMBL BC133050; AAI33051.1; -; mRNA RefSeq NP_066544.1; NM_021066.2; . UniGene Hs.406691; -; . UniGene Hs.734717; -; . ProteinModelPortal Q99878; -; . SMR Q99878; -; . BioGrid 113927; 10; . IntAct Q99878; 16; . MINT MINT-3060013; -; . STRING 9606.ENSP00000328484; -; . iPTMnet Q99878; -; . PhosphoSitePlus Q99878; -; . SwissPalm Q99878; -; . BioMuta HIST1H2AJ; -; . DMDM 12585257; -; . SWISS-2DPAGE P99059; -; . EPD Q99878; -; . MaxQB Q99878; -; . PaxDb Q99878; -; . PeptideAtlas Q99878; -; . PRIDE Q99878; -; . TopDownProteomics Q99878; -; . DNASU 8331; -; . Ensembl ENST00000333151; ENSP00000328484; ENSG00000276368; . GeneID 8331; -; . KEGG hsa:8331; -; . UCSC uc003njn.2; human; . CTD 8331; -; . GeneCards HIST1H2AJ; -; . HGNC HGNC:4727; HIST1H2AJ; . HPA HPA041189; -; . MIM 602791; gene; . neXtProt NX_Q99878; -; . OpenTargets ENSG00000276368; -; . PharmGKB PA29104; -; . eggNOG KOG1756; Eukaryota; . eggNOG COG5262; LUCA; . GeneTree ENSGT00760000118934; -; . HOGENOM HOG000234652; -; . HOVERGEN HBG009342; -; . InParanoid Q99878; -; . KO K11251; -; . OMA GICQEAT; -; . OrthoDB EOG091G0XGD; -; . PhylomeDB Q99878; -; . TreeFam TF300137; -; . Reactome R-HSA-1221632; Meiotic synapsis; . Reactome R-HSA-171306; Packaging Of Telomere Ends; . Reactome R-HSA-201722; Formation of the beta-catenin:TCF transactivating complex; . Reactome R-HSA-212300; PRC2 methylates histones and DNA; . Reactome R-HSA-2299718; Condensation of Prophase Chromosomes; . Reactome R-HSA-2559580; Oxidative Stress Induced Senescence; . Reactome R-HSA-2559582; Senescence-Associated Secretory Phenotype (SASP); . Reactome R-HSA-2559586; DNA Damage/Telomere Stress Induced Senescence; . Reactome R-HSA-3214815; HDACs deacetylate histones; . Reactome R-HSA-3214847; HATs acetylate histones; . Reactome R-HSA-3214858; RMTs methylate histone arginines; . Reactome R-HSA-427359; SIRT1 negatively regulates rRNA Expression; . Reactome R-HSA-427389; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; . Reactome R-HSA-427413; NoRC negatively regulates rRNA expression; . Reactome R-HSA-5250924; B-WICH complex positively regulates rRNA expression; . Reactome R-HSA-5334118; DNA methylation; . Reactome R-HSA-5578749; Transcriptional regulation by small RNAs; . Reactome R-HSA-5617472; Activation of anterior HOX genes in hindbrain development during early embryogenesis; . Reactome R-HSA-5625886; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; . Reactome R-HSA-5689603; UCH proteinases; . Reactome R-HSA-5689880; Ub-specific processing proteases; . Reactome R-HSA-5689901; Metalloprotease DUBs; . Reactome R-HSA-606279; Deposition of new CENPA-containing nucleosomes at the centromere; . Reactome R-HSA-73728; RNA Polymerase I Promoter Opening; . Reactome R-HSA-73777; RNA Polymerase I Chain Elongation; . Reactome R-HSA-912446; Meiotic recombination; . Reactome R-HSA-977225; Amyloid fiber formation; . ChiTaRS HIST1H2AJ; human; . GeneWiki HIST1H2AJ; -; . GenomeRNAi 8331; -; . PRO PR:Q99878; -; . Proteomes UP000005640; Chromosome 6; . Bgee ENSG00000182611; -; . CleanEx HS_HIST1H2AJ; -; . Genevisible Q99878; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0000790; C:nuclear chromatin; IBA:GO_Central; . GO GO:0000786; C:nucleosome; IEA:UniProtKB-KW; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0003677; F:DNA binding; IBA:GO_Central; . GO GO:0006342; P:chromatin silencing; IBA:GO_Central; . Gene3D 1.10.20.10; -; 1; . InterPro IPR009072; Histone-fold; . InterPro IPR002119; Histone_H2A; . InterPro IPR007125; Histone_H2A/H2B/H3; . InterPro IPR032454; Histone_H2A_C; . InterPro IPR032458; Histone_H2A_CS; . Pfam PF00125; Histone; 1; . Pfam PF16211; Histone_H2A_C; 1; . PRINTS PR00620; HISTONEH2A; . SMART SM00414; H2A; 1; . SUPFAM SSF47113; SSF47113; 1; . PROSITE PS00046; HISTONE_H2A; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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